Roberto Martinez makes seven changes from the side that beat Huddersfield Town in the 5th round of the FA Cup last weekend and Antolin Alcaraz is included on the bench for the first time since September 2012.
Reading: Federici, Kelly, Harte, Mariappa, Morrison, Karacan, Leigertwood, Akpan, Kebe, McAnuff, Pogrebnyak
Subs: Taylor, Shorey, Pearce; McCleary, Robson-Kanu, Hunt, Le Fondre
Latics: Al Habsi, Kone, McCarthy, Caldwell (c), Di Santo, Maloney, McArthur, Boyce, Beausejour, Figueroa, Scharner
Subs: Robles, Stam, Alcaraz, Espinoza, Gomez, McManaman, Henriquez